Tests to Support Product Claims for Efficacy

Mildness


XtraMild Mildness to Skin

Mildness to Eye

Collagen Boosting


Collagen Boosting Test - Sirius Red Assay Test

Collagen Boosting Test - qPCR test

Antioxidant Activity


Antioxidant Activity Test - In Chemico

Antioxidant Activity Test - OxiSelect

Pigmentation


Skin Pigmentation Test

Custom Claims Testing Available

We often develop bespoke adaptations to support your unique product claims – please consider our

Bespoke Testing Available

Not Sure What You Need?

Get in touch with us and we’ll be happy to signpost you.

Contact Us
OECD Approved Regulatory Testing
Non-Regulatory Safety Testing

GLP Skin Tests


Skin irritation OECD TG439

Skin Corrosion OECD TG431

KeratinoSens OECD TG442d

GLP Eye Tests


Eye Irritation OECD TG492

Eye Hazard Identification OECD TG492B

Skin Tests


Skin Irritation ET50

XtraMild Mildness to Skin

GARD skin test

Phototoxicity

Eye Tests


Eye Irritation ET50

Oral/mucosal Tests


Oral Irritation ET50

Gingival Irritation ET50

Vaginal Irritation Test

Systemic/cellular Tests:


Cytotoxicity

ISO 10993-5 Cytotoxicity

Acute Toxicity (AcutoX)

Inhalation Toxicity

Need Something Different?

Please consider our

Bespoke Testing Available

if your specific needs are not met by these tests.

Not Sure What You Need?

Get in touch with us and we’ll be happy to signpost you.

Contact Us

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OECD TG 439: How Skin Irritation Testing Moved Off Animals

OECD TG 439: How Skin Irritation Testing Moved Off Animals

by Tyler Sear | Aug 11, 2026 | Animal-free testing, News, XCellR8 News

We’re doing something a bit different over the next few weeks. We’ve been asked more than once recently to explain what actually sits behind the regulatory tests we run, so we’re working through our safety testing suite one guideline at a time: where...
Antioxidant Testing: Capacity, Mechanism and What Happens in Cells

Antioxidant Testing: Capacity, Mechanism and What Happens in Cells

by Tyler Sear | Aug 6, 2026 | Animal-free testing, News, XCellR8 News

Not all antioxidants work in the same way, and not every antioxidant claim is supported by the same level of evidence. A single test result can suggest strong antioxidant activity while revealing very little about how an ingredient works, whether it performs in a...
The Rise of the Skintellectual: Why Claims Matter More Than They Used To

The Rise of the Skintellectual: Why Claims Matter More Than They Used To

by Tyler Sear | Aug 5, 2026 | Animal-free testing, News, XCellR8 News

Something has shifted in the way people buy skincare. Ingredient lists get picked apart on TikTok. Cosmetic chemists have built large followings explaining what actives do and, just as often, what they don’t. A consumer who has never set foot in a lab can now...
The Evidence-Building Strategy Brands Are Missing

The Evidence-Building Strategy Brands Are Missing

by Tyler Sear | Aug 3, 2026 | Animal-free testing, Compliance & regulation, News, XCellR8 News

Most brands face a common challenge with claims support: either they dive straight into expensive, time-intensive testing, or they hesitate entirely, assuming the process will be prohibitively complex. Both approaches miss an opportunity to build defensible claims...
Surfactant Mildness: How to Optimise Your Blend

Surfactant Mildness: How to Optimise Your Blend

by Tyler Sear | Jul 29, 2026 | Animal-free testing, Compliance & regulation, News, XCellR8 News

Formulating a cleansing product means solving an age-old problem: the surfactants that clean and foam best are often the ones that irritate skin most. But the real problem isn’t the trade-off itself. It’s the lack of data to optimise it. Here’s what...
Proving Barrier Repair: How to Substantiate What Your Product Actually Does

Proving Barrier Repair: How to Substantiate What Your Product Actually Does

by Tyler Sear | Jul 23, 2026 | Animal-free testing, Compliance & regulation, News, XCellR8 News

Every beauty brand now claims to “repair,” “strengthen,” or “restore” the skin barrier. But how many can actually prove it? Formulators face a practical problem: they can describe the problem (damaged barrier, dehydrated, irritated...
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