XCellR8’s antioxidant test uses the OxiSelect™ method. The test is based on the intracellular conversion of DCFH to its fluorescentmetabolite (DCF). The reaction is inhibited by anti-oxidants, reducing the amount of fluorescence observed and so the test measures fluorescent intensity. You can read more information about OxiSelect™ here.
This depends on whether you need the test for EU regulatory purposes, in which case Skin Irritation OECD TG 439 might be right for you, providing a binary answer as to whether your item is an Irritant or Non Irritant, or for product development. Our non regulatory test uses the ET50 method and is used to place your item into a rank order of irritation potential or compare it against industry benchmarks. We’re more than happy to chat through the different test methods, or can introduce you to one of our regulatory consultancy partners who can help you make the decision.
Yes. In these circumstances, we will usually issue the invoice at the beginning of the study and ask for payment within 30 days.
XCellR8’s tests can take as little as 4 weeks, up to a maximum of 12 weeks. We’ll always try our best to accommodate urgent requests. Please do bear in mind that the timeframe starts at the point we receive your sample and the accompanying information that we ask for in order to start a study, and finishes when we send your draft report.
We ask for an expiry or retest date to ensure that your test item is within its established shelf life specifications when stored under defined conditions – it’s all part of our work being performed in line with GLP (Good Laboratory Practice). It’s important that this is a true expiry date or retest date as it helps us make sure your test item is behaving as it should, and the results you get from us are correct.
Broadly speaking, assay is a scientific term that means test. It is often used by the pharmaceutical industry to describe the experimental procedure that quantitatively or qualitatively measures the presence, amount, or functional activity of a target entity (to get all Wikipedia about it!)