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Frequently Asked Questions

Which skin sensitisation test do I need?

Current regulatory guidance for in vitro skin sensitisation testing is to adopt the “2 out of 3” approach, whereby 2 positive results out of the 3 tests (OECD TGs 442c, 442d and 442e) results in classification as a Skin Sensitiser. If you perform two of the tests and get matching results, this strategy states you can have confidence in the result without the third test. If they have different results, proceed to the third method to find a definitive result. Each of the three methods has different requirements regarding the solubility of your test item, so contact us to find out which will be best for you. You can also read more about the test methods here.

How much of my product or material will you need to start a study?

10 ml if it’s a liquid or 10g if it’s a solid. This makes sure we’ve got enough of the item if you order more than one test. Please ensure your samples are clearly labelled, and match any documentation you send with them. If you don’t have this amount of your test item available, please call us to discuss your options.

We don’t use a Purchase Order system or else Purchase Orders take a long time to issue in my organisation. Can I still start my study?

Yes. In these circumstances, we will usually issue the invoice at the beginning of the study and ask for payment within 30 days.

Does XCellR8 offer human patch testing?

No, we don’t but many clients use our in vitro tests as an early screen in product development before they get to more expensive human trials. They can also be used to generate supporting information in a weight-of-evidence approach to safety assessment. XCellR8’s tests may give you a binary classification on the effect of an ingredient, for example, Irritant or Non Irritant, or a more detailed classification to help you rank irritation potential. Please get in touch if you’d like to find out more.

Do you offer work placements or internships?

We don’t have an internship programme at the moment but do offer occasional work placements to university students who are interested in animal-free test methods. If you would like to apply, please send your CV and a covering email explaining what our values mean to you to info@x-cellr8.com.

When will I receive my final report?

Most of our tests take 6-8 weeks from receipt of your sample to the first draft report, although please note sometimes it can be slightly shorter or longer depending on the test. We ask for your comments on the draft report within a week, and your final report will be with you after we’ve then completed our final QA checks.