The place to start is to establish if you need the test results as part of a regulatory submission, or whether you want to discover a substance’s properties as part of a product development or pre-clinical programme. We’re always happy to advise before you start so please feel free to call if you’re unsure.
Noting the purity of the item being tested is part of our GLP (Good Laboratory Practice) compliance. For certain tests, it allows us to ensure the correct concentration is being tested. It’s also another piece of key information that we check to make sure we have the right test item, and you get the right result.
We don’t provide the Ames test, as it uses animal components. We do provide the BlueScreen assay, a genotoxicity test that covers all types of genotoxicity: anugens, clastogens, and mutagens.
We ask for an expiry or retest date to ensure that your test item is within its established shelf life specifications when stored under defined conditions – it’s all part of our work being performed in line with GLP (Good Laboratory Practice). It’s important that this is a true expiry date or retest date as it helps us make sure your test item is behaving as it should, and the results you get from us are correct.
Current regulatory guidance for in vitro skin sensitisation testing is to adopt the “2 out of 3” approach, whereby 2 positive results out of the 3 tests (OECD TGs 442c, 442d and 442e) results in classification as a Skin Sensitiser. If you perform two of the tests and get matching results, this strategy states you can have confidence in the result without the third test. If they have different results, proceed to the third method to find a definitive result. Each of the three methods has different requirements regarding the solubility of your test item, so contact us to find out which will be best for you. You can also read more about the test methods here.
Please send any media or study requests to email@example.com for the attention of our Marketing Director, Susie Lee-Kilgariff.