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Beyond the Ethics: In Pursuit of Science

Beyond the Ethics: In Pursuit of Science

by Sam Thistleton | Oct 15, 2021 | Animal-free testing, In Vitro Safety, News

The blog this week talks about the reasons why animal testing is considered out-dated from a scientific perspective, and the advantages of the modern animal-free alternatives. An article in Food and Chemical Toxicology all the way back in 1985 questions the scientific...
Skin sensitisation and preservatives: Achieving more human-relevant safety evaluations

Skin sensitisation and preservatives: Achieving more human-relevant safety evaluations

by Carol Treasure | Oct 15, 2020 | Animal-free testing, In Vitro Safety, News

This article first appeared in HPC Today Magazine, September 2020 which can be viewed here. Abstract Preservatives in cosmetics are well known skin sensitisers and a common cause of allergic contact dermatitis. Annex V of Cosmetics Regulation EC 1223/2009 lists 57...
XCellR8’s DPRA skin sensitisation test achieves registration with The Vegan Society

XCellR8’s DPRA skin sensitisation test achieves registration with The Vegan Society

by Minty Hand | Jan 15, 2020 | Animal-free testing, News, XCellR8 News

Following a robust, independent audit, XCellR8’s Direct Peptide Reactivity Assay (DPRA) skin sensitisation test has been registered with The Vegan Society. The test joins 40,000 other registered vegan products but only a handful of safety tests, and is the only...
3 Regulatory in vitro skin sensitisation tests explained

3 Regulatory in vitro skin sensitisation tests explained

by Minty Hand | Dec 19, 2018 | Animal-free testing, In Vitro Safety

The complex pathway of skin sensitisation has been considered difficult to model in vitro: how could such an intricate, multi-step, physiological pathway be accurately represented in a single test? Thanks to the significant efforts of multiple scientific groups over...

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Tel: +44 (0)1925 607 134
Registered number: 6489519
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  • About Us
    • Donate to XCellR8
    • What we do
    • Meet the team
    • Why choose animal-product-free?
    • GLP accreditation
    • Research & development
    • Work for us
    • Back
  • Regulatory Safety Testing
    • Regulatory compliance
      • REACH compliance
      • CLP regulation
      • Cosmetics Regulation
      • Back
    • Skin Sensitisation Testing
      • DPRA OECD TG 442c
      • KeratinoSens OECD TG 442d
      • h-CLAT OECD TG 442e
      • Back
    • Eye Irritation Testing
      • Eye Irritation OECD TG 492
      • Ocular Irritection OECD TG 496
      • Back
    • Skin Irritation OECD TG 439
    • Skin Corrosion OECD TG 431
    • Back
  • Non-regulatory Testing
    • Skin irritation ET50
    • XtraMild Mildness to skin
    • Eye irritation ET50
    • Oral irritation ET50
    • Gingival irritation ET50
    • GARDskin test
    • Cytotoxicity
    • ISO 10993-5 Cytotoxicity
    • Genotoxicity
    • Micronucleus Test
    • Acute toxicity
    • Inhalation toxicity
    • Phototoxicity
    • Vaginal irritation test
    • Back
  • Customised Testing
  • Who We Help
    • Cosmetics and Personal Care
      • Anti-oxidant activity
      • XtraMild
      • Mildness to eye
      • Back
    • Household and industrial chemicals
    • Safety consultancies and CROs
    • Client case studies
    • Back
  • Knowledge Hub
    • News
    • Blogs
    • Events
    • Newsletter Sign Up
    • FAQs
    • Press Room
    • Back
  • Contact us